This online interactive resource (http://stickleback.genomezoo.net) is created to allow easy navigation of mRNA expression profiles and provides a comprehensive annotation of differentially expressed stickleback genes. Using stickleback as a model organism, we employ high-throughput sequencing technologies to identify and study mRNA-based gene regulatory mechanisms in response to salinity. This website is meant to facilitate easy access to our published data sets as well as some unpublished information.